The Algerian Cardiac Surgeon
Volume 1, Numéro 1, Pages 67-73
2025-02-01
Anesthésie Chez Les Drépanocytaires Candidats à Une Chirurgie Cardiaque
Auteurs : Haneche Hynda . Boukhmis Abdelkader . Allaoui Atika . Aitmohand Rachid . Bekai Yacine . Khichane Malika . Hamzaoui Azzedine . Djafer Boulanouar .
Résumé
Sickle cell disease is a genetic hemoglobinopathy characterized by a pathological hemoglobin Hb S responsible for a process of polymerization under conditions of deoxygenation. It is manifested by anemic episodes, vaso-occlusive crises, severe infectious syndromes and multiple functional degenerations. Surgery exposes these patients to a relatively higher risk of perioperative mortality. The cardiac surgery is particularly high-risk, as extracorporeal circulation is a major factor in falciformation. Perioperative management requires multidisciplinary consultation and the development of transfusion or exchange transfusion protocols to reduce the concentration of Hemoglobin S concentration below the threshold.
Mots clés
Sickle Cell Disease, Cardiopulmonary Bypass, Anesthesia, Cardiac Surgical Procedures
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