Batna Journal of Medical Sciences
Volume 11, Numéro 1, Pages 1-9
2026-03-02
Epidemiological, Diagnostic, And Therapeutic Aspects Of Community-acquired Complicated Intra-abdominal Infections At The University Hospital Center Of Constantine, Algeria.
Authors : Charaoui Khalida . Boulakehal Nadia . Bouchair Zoheir . Belmir Ali . Kaoueche Omar . Benlabed Kaddour . Kara-mostefa Rafik .
Abstract
Introduction and objectives: Intra-abdominal infections are the leading non-traumatic surgical emergencies, with persistently morbidity and mortality remain high. The objective of our work is to report the epidemiological-clinical, diagnostic, and therapeutic aspects of complicated community-acquired intra-abdominal infections in adults. Patients and methods: A prospective, descriptive study was conducted from September 2016 to March 2018 on a cohort of adult patients who underwent surgery for community-acquired complicated IAI. Data were collected using survey forms. Epidemiological, clinical, biological, radiological, therapeutic, and evolutionary variables were described. Results: 227 patients were recruited. Average age 44±20 years [15 to 90 years]. Sex ratio of 1.9. 26% of patients had at least one comorbidity. The most frequent symptoms were abdominal pain (99%), signs of peritoneal irritation (89%), clinical presentation of acute appendicitis (56%), nausea and/or vomiting (46%). An occlusive syndrome (22%). Fever was present in 45% of the patients, 7% of the patients had signs of severity at admission. The source of contamination was appendicular in more than 50% of cases. Empirical antibiotic therapy consisted of cefazolin in 75% of cases; 49% received triple therapy with gentamicin and metronidazole, and 25% of cases were in dual therapy with metronidazole. Cefotaxime was prescribed in severe cases or in the presence of comorbidities. The peritoneal fluid culture was positive in 58% of cases. Escherichia coli was isolated in 51% of cases. The mortality rate was 15.4%. Discussion and conclusion: Intra-abdominal infections were of appendicular origin in more than half of the cases in our series. Mortality was associated with advanced age, the presence of comorbidities, the severity of the initial clinical presentation, and a colorectal origin of the infection.
Keywords
intra-abdominal infections ; epidemiology ; diagnosis ; empirical antibiotic therapy ; microbiology
Les articles similaires
بوسالم أحلام
.
عابد يوسف
.
ص 117-132.
Yahia Zeghoudi
.
pages 74-88.
Benelmouffok Souheila
.
pages 181-190.
Said Houari Amel
.
pages 257-268.
