Batna Journal of Medical Sciences
Volume 13, Numéro 6, Pages 438-443
2026-07-01

Splenic Infarction As A Sentinel Sign Of Underlying Pathology: Clinical Insights From A Seven-patient Series

Authors : Guettaf Imane . Rechach Adel . Charifi Meriem . Djouhri Messaouda . Oukd Ali Souraya . Chibane Ahcene .

Abstract

Splenic infarction (SI) is a rare condition characterized by vascular compromise leading to splenic parenchymal ischemia and necrosis. Its diagnosis is often challenging due to nonspecific clinical presentation, which may include left upper quadrant abdominal pain, fever, or constitutional symptoms. Diagnosis relies predominantly on contrast-enhanced computed tomography (CT), which typically demonstrates characteristic wedge-shaped hypodense lesions oriented toward the splenic hilum. SI often reveals severe underlying conditions, including malignancies, hematologic disorders, or cardioembolic events. Recent studies indicate an incidence of approximately 0.016% in hospital admissions, with thromboembolic and hematologic etiologies being predominant. Therapeutic strategies are not standardized and require etiology-specific management, often involving supportive care, anticoagulation for thromboembolic causes, and treatment of the underlying disorder. This report describes a series of seven patients diagnosed with SI. The study focuses on the analysis of medical records of patients hospitalized for splenic infarction between 2016 and 2025

Keywords

Splenic infarction ; Inflammatory disease ; Metabolic disease ; Hematologic disorde ; Thromboembolic event