Batna Journal of Medical Sciences
Volume 13, Numéro 8, Pages 570-574
2026-07-30

Safety And Diagnostic Yield Of Pediatric Renal Biopsy In An Adult Nephrology Setting: A Single-center Experience From Algiers, Algeria



Authors : Arzour Hind . Gherib Lynda . Bahriz Mohamed Rachid . Rabhia Mehdi . Saad Djaballah Djihad . Azouaou Sabrina . Daghor-abbaci Karima . Baghdali Feriel Yasmine . Sai Ryma . Haddouche Assia . Chouli Mohamed . Alghazali Ahlem . Laouar Leila . Belbouab Reda . Salah Sofiane Samir . Haddoum Farid .

Abstract

Abstract: Introduction: Percutaneous renal biopsy (PRB) is crucial for accurate diagnosis in pediatric nephrology, especially for atypical or resistant nephrotic syndromes. Our study aims to describe the epidemiological, clinical, and histopathological characteristics of Algerian children who underwent PRB in our unit to evaluates the tolerance and safety of this procedure performed under local anesthesia. Methods: We conducted a retrospective descriptive study at Mustapha Bacha University Hospital, including 104 children (2 months–16 years) referred for PRB between March 2018 and June 2024. The procedure was performed by experienced adult nephrologists, systematically under local anesthesia (Lidocaine). Demographic, clinical, histological, and tolerance data were analyzed. Results: Eighty-four children underwent PRB (mean age: 11.3 years; male predominance: 63.4%). The main indication was atypical or steroid-resistant nephrotic syndrome (78.4%). The predominant histological lesions were Minimal Change Disease (MCD) (36.5%), followed by Lupus Nephritis (17.3%) and Focal Segmental Glomerulosclerosis (FSGS) (15.4%). Twenty-six percent of patients were steroid-resistant. The noticeable presence of MCD within this subgroup reflects the selection bias inherent to the biopsy indications. PRB demonstrated excellent tolerance, with only 4.8% minor complications (transient hematuria, hematoma) and no major complications reported. Conclusion: Pediatric PRB performed in an adult unit under local anesthesia is a feasible, safe, and diagnostically relevant procedure for characterizing the spectrum of pediatric nephropathies in Algeria. This organizational setup serves as a pragmatic model for resource-constrained tertiary centers, yielding results comparable to regional series.

Keywords

Percutaneous renal biopsy ; Child ; Atypical nephrotic syndrome ; Local anesthesia ; Minimal change disease

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