e-Algerian Journal of Health & Research
Volume 2, Numéro 2, Pages 10-20
2026-04-26

Synchronous Acute Suppurative Appendicitis In Two Brothers: A Rare Case Report And Review Of The Literature



Authors : Taha Mohamed . Alkhalifamohamed Hussam . Omar Amany . Moidum Fazil . Abdalla Eltayeb . Mahmoud Esra .

Abstract

Background: Acute appendicitis is the most common surgical emergency in children and adolescents, yet simultaneous presentation in siblings is extremely rare. Most published reports involve monozygotic twins, emphasizing genetic susceptibility. Case Presentation: We describe two non-twin brothers, aged 15 and 9 years, who developed acute appendicitis on the same day. Both presented with abdominal pain and right iliac fossa tenderness. Laboratory evaluation demonstrated neutrophilia and elevated inflammatory markers. Imaging confirmed appendicitis in both, with an appendicolith in the younger brother. Both underwent laparoscopic appendectomy, and histopathology revealed acute suppurative appendicitis with peri-appendicitis. Their postoperative recoveries were uneventful. Discussion: Previous reports of synchronous appendicitis have largely involved monozygotic twins. Familial clustering across siblings has also been described, but usually over several years rather than acutely. Our cases are unique in documenting synchronous appendicitis in two brothers of different ages, one of whom had a recent episode of acute otitis media. These findings support the possibility of post-infectious or immune-mediated triggers acting upon a background of familial susceptibility. Conclusion: Synchronous appendicitis is not limited to twins. Clinicians should maintain a high index of suspicion when evaluating abdominal pain in siblings, especially in the context of recent infection and positive family history. Early diagnosis and timely surgical intervention are essential to prevent morbidity.

Keywords

acute appendicitis ; familial aggregation ; synchronous presentation ; appendicolith ; case report

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