REVUE ALGERIENNE D’ALLERGOLOGIE
Volume 9, Numéro 2, Pages 13-21
2024-12-19

Profil Des Patients Avec Ulcères Digitaux Au Cours De La Sclérodermie Systémique à L’est Algérien



Auteurs : Benmostefa Nouria . Roula Daoud . Slimani Samy . Rouabhia Samir . Malek Rachid . Mouthon Luc .

Résumé

We studied the particularities of the Algerian population suffering from systemic sclerosis (SSc) with and without digital ulcers (DU), by comparing the two groups. The patients were recruited from internal medicine, rheumatology and dermatology in eastern Algerian university hospitals. Patients had to meet the 2013 ACR/EULAR criteria. The epidemiological, clinical and immunological characteristics as well as the treatments prescribed for the 2 groups were compared. The Arab hand Functional Index, the Health Assessment Questionnaire and the Hospital Anxiety and Depression Scale were used to assess hand disability, overall disability and the degree of anxiety and depression, respectively. Around a hundred patients with SSc were included in the study. Patients with DU had more telangiectasia (p=0.004), pitting scars (p=0.01) and had a sPAP greater than 35 mm Hg (p=0.01). On the skin level, they were more diffuse form (p<0.0001), had a higher modified Rodnan skin score (p<0.0001), developed more calcinosis than patients without DU (<0.0001) and had more tendon retractions. Regarding treatment, DU received more Bosentan than patients without DU (p<0.01). Patients with DU had more reduced manual mobility (p<0.0001), greater manual and overall disability (p<0.0001). Patients from eastern Algeria suffering from SSc with DU are associated with more severe skin and vascular involvement and are the cause of greater manual and overall disability.

Mots clés

systemic sclerosis ; digital ulcers

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